5 Essential Elements For cees dekker

5 Essential Elements For cees dekker

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2009, discovery of a new phenotype for germs in slim nanofluidic slits; and 1st detection of community protein buildings along DNA using strong-state nanopores

Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular types with recombination operate.

Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I

Since 2000, Dekker has shifted the key aim of his function toward biophysics where by he scientific studies the Houses of one biomolecules and cells utilizing the resources of nanotechnology. This variation of industry was pushed by his fascination for the exceptional operating of Organic molecular structures, in addition to through the very long-time period standpoint that many intriguing discoveries might be envisioned During this field.[5] Present traces of investigation in his biophysics team are from the parts of:[six]

That is a aspiration of mine and we established to work by using a delicious dose of naivety. This is certainly something that will probably generate spectacular leads to the for a longer period term, but that does not subject. You should not only want to work about the thoughts of tomorrow, but additionally to the questions from the day immediately after tomorrow.’

Our analysis ranges from your biophysics of DNA to synthetic cells and past. Make sure you have a look beneath in the spectrum of our present tasks.

‘At the beginning we looked at biological devices having a Bodily perspective and acted on the basis in the applications we knew. It took a couple of years in advance of we started off Functioning extra on the big biological challenges. I then began to connect with it nanobiology, a term that did not exist at enough time.

2000, discovery that nanotubes can carry amazing large recent densities; resolved the controversial situation of Digital transport by way of DNA molecules by measurements of insulating actions at the single molecule degree; and demonstration of the AFM technique for single-molecule manipulation of nanotubes

In 1993, like a youthful and keen associate professor at Delft University of Technological innovation, I'd initially targeted the investigation endeavours of my group on measuring the electrical conductance of just one conducting-polymer molecule. In two years, we had developed a tool where only one wire of a phthalocyaninepolysiloxane polymer was connected among two carefully spaced metallic nanoelectrodes.

But carbon nanotubes have remained a exploration matter of significant curiosity to numerous. Indeed, the outlook on using carbon nanotubes to make simple equipment, in parts for example radio-frequency electronics, digital electronics and flexible electronics, stays vibrant.

Example (four) of bending configurations in 3D simulations of DNA rods ceesdekker.net on nanopores. A part of the membrane is proven in grey, the rim of your pore is highlighted in purple, plus a 3D rendering from the movement with the DNA rod is displayed.

Afterwards we spoke once again briefly mainly because Dekker felt that our dialogue of his religion rapidly grew to become purely philosophical, While What's more, it concretely helps him in his function.

Let’s very first search back again in the intervening time when you decided to shift your concentrate from superconductivity and nanotubes to biology at the end of the 1990s.

Supercoiling-dependent DNA binding: quantitative modeling and purposes to bulk and solitary-molecule experiments